LSUHSC is hosting a free study for adults with well-controlled asthma as part of the American Lung Association’s Long-acting Beta Agonist Step-Down Study (LASST). People 18 years of age and older who have controlled asthma are encouraged to call 504-568-3450 for more information.
With the high cost of medicine, patients have been known to lower their own dosages as their health improves in order to save money. LASST seeks to study various treatment plans as a way to safely decrease dosages of asthma medication over time. Below is the description of LASST as presented on the American Lung Association website:
“Current asthma guidelines recommend stepping down therapy once asthma is controlled for at least three months. For patients treated with inhaled corticosteroids (ICS) alone, a dose reduction of 25–50 percent to a minimal dose that controls disease is established. However, the optimal approach to reducing treatment in patients with asthma that is well controlled on fixed dose combination ICS/LABA (long-acting beta agonists) is not clear. The study will compare three approaches of care to patients with asthma well controlled for three months on combination ICS/LABA therapy: reduction of ICS dose and maintenance of LABA, initial discontinuation of LABA with continuation of ICS and continuation of stable dose ICS/LABA. The data will allow the determination of the optimal treatment strategy defined as that which results in the lowest rate of treatment failure over 48 weeks of follow up. Additional exploratory analyses will include assessing risk factors for step-down failure and assessing the optimal duration of time that asthma control should be maintained before therapy is reduced.”